Meaning of homodeletion | Babel Free

Definitions

A type of chromosomal deletion where both copies (alleles) of a particular DNA sequence are lost from an individual's genome.

countable, uncountable

Examples

“The study identified a homodeletion in the CDKN2A gene, which is associated with an increased risk of certain cancers.”

“Define homodeletion as an operation of deleting a run of the same nucleotide and homoinsertion as an operation of inserting a run of the same nucleotide.”

“While homodeletion of CYB5D2 can be detected in both the TCGA (8/1093=0.7%) and Metabric (4/2051=0.2%) datasets, the frequency is low; nonetheless, in both cohorts homodeletion in TP53 was not detected.”

“These tumors often harbor homodeletion of Hippo core suppressors.”

CEFR level