Meaning of senolysis | Babel Free

Definitions

The destruction of senescent cells, such as to alleviate age-related diseases.

countable, uncountable

Equivalents

Examples

“2020, Joanne Laycock, et al., 7: The Role of Chronic Kidney Disease in Ectopic Calcification, Elena Aikawa, Joshua D. Hutcheson (editors), Cardiovascular Calcification and Bone Mineralization, Springer (Humana Press⟳), page 156, These strategies consist⟳ of senolysis, immune-mediated senescent cell clearance and SASP neutralisation.”

“2022, Franziska Kellers, et al., Senescence-Associated Molecules and Tumor-Immune-Interactions as Prognostic Biomarkers in Colorectal Cancer, Arndt Hartmann, Luca Di Tommaso (editors), Rising Stars 2021: Pathology, Frontiers in Medicine, page 46, This immune cell-mediated senolysis seems to be facilitated via direct⟳ cell-cell contact⟳ inducing apoptosis and granule exocytosis.”

“2023, Jan O. Nehlin, Chapter 7: Senolytic and senomorphic interventions to defy senescence-associated mitochondrial dysfunction, Ufuk Çakatay, Mehmet Can Atayik (editors), Advances in Protein Chemistry and Structural Biology, Volume 135, Elsevier (Academic Press⟳), page 224, Senolytics are compounds that target⟳ selectively senescent cells and induce their lysis, a process⟳ known as senolysis. Senescent cells are resistant to apoptosis because they have⟳ an increase⟳[d] expression of pro-survival networks.”

CEFR level