Meaning of intrabody | Babel Free

Definitions

An antibody that exists inside and operates within a cell.

Examples

“1998, Discover, Volume 19, Time Inc., page 36, The T cells could now produce their own anti-Tat intrabody.”

“2006, HIV Molecular Immunology, Volume 2, Los Alamos National Laboratory (Theoretical Biology and Biophysics Group T-10), page 902, Single chain antibodies, intrabodies, were engineered that can be stably expressed in the cytoplasm of mammalian cells […] .”

“2009, Laurence Guglielmi, Pierre Martineau, Intrabody Expression in Eukaryotic Cells, Robert Aitken (editor), Antibody Phage Display, Springer (Humana Press), page 196, Even when aggregated, some intrabodies may retain the capacity to sequester the target antigen, preventing it from reaching its intended cellular location and thereby inhibiting its function (2–3).”

CEFR level