Meaning of intrabody | Babel Free

Definitions

An antibody that exists inside and operates within a cell.

Examples

“1998, Discover⟳, Volume 19, Time Inc., page 36, The T cells could now produce⟳ their own⟳ anti-Tat intrabody.”

“2006, HIV Molecular Immunology, Volume 2, Los Alamos National Laboratory (Theoretical Biology and Biophysics Group T-10), page 902, Single chain antibodies, intrabodies, were engineered that can be stably expressed in the cytoplasm of mammalian cells […] .”

“2009, Laurence Guglielmi, Pierre Martineau, Intrabody Expression in Eukaryotic Cells, Robert Aitken (editor), Antibody Phage Display, Springer (Humana Press⟳), page 196, Even when aggregated, some intrabodies may retain⟳ the capacity to sequester the target⟳ antigen, preventing it from reaching its intended cellular location and thereby inhibiting its function (2–3).”

CEFR level