Meaning of craniorachischisis | Babel Free

Definitions

A lethal defect of the neural tube in which both the brain and spinal cord are left open.

Equivalents

Examples

“Craniorachischisis is a variant of rachischisis that occurs when the entire spinal cord and brain are exposed – simultaneous complete⟳ rachischisis and anencephaly.^([Wikipedia])”

“Craniorachischisis and anencephaly represent⟳ the most extensive of the neural tube defects. In craniorachischisis the neural tube from the midbrain down to the upper sacral region of the spinal cord remains open⟳ (Fig. 26.1), there being no fusion of the tube.”

“The neural tube closure occurs around day 28 after conception; its closure failure may result⟳ in a defect that can range from anencephaly, incompatible with life, to small meningoceles.[1] The definition of neural tube defects (NTD) include⟳ anencephaly, craniorachischisis, iniencephaly, meningocele, meningomyelocele, and encephalocele, but not isolated findings of hydrocephalus or spina bifida oc[c]ulta.[1] Iniencephaly, from the ancient Greek "inion" meaning "nape of the neck", had its first report⟳ by Saint-Hilaire in 1836,[2] is characterized by a variable defect of the occipital bone, resulting in a large foramen magnum; partial or total absence of the cervical and thoracic vertebrae with irregular melting of those present⟳, accompanied by incomplete closure of arcs and/or vertebral bodies, marked lordosis, hyperextension of the cervicothoracic spine; and a face⟳ deflected up.[3] The incidence is about 1:1000–1:2000 births,[4] then is a pretty rare NTD.”

“Craniorachischisis is readily diagnosed using ultrasound. However, it can be confused with other defects involving the brain – anencephaly, acrania or amniotic band syndrome.”

CEFR level